Article

2008-02-01 International-UN-NGOs

People who got AIDS vaccine more likely to become infected with HIV

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Posted by phil_b 2008-02-01 02:06|| || Front Page|| [3 views ] Top

#1 Given that we know so much about what this vaccine does in animals, it would be useful to see what it can do in people,'' he said in a telephone interview. ``I don't think the T-cell vaccines are dead because of this.''

This is exactly the reason that it is too bad that they will be limiting the human studies. It is a difficult problem in that obviously you don't want to test products that will make people more prone to getting the HIV virus. But what good is it to test animals if there is no way to transfer the knowlege to human subjects?

Posted by Elminetle Panda5853 2008-02-01 02:25|| 2008-02-01 02:25|| Front Page Top

#2 Merck halted a study, called STEP, in September after an unanticipated finding: people who got the vaccine were more likely to contract HIV than those who didn't.

I suppose there was a control group who didn't get the vaccine, and that they fared significantly better?

Posted by gorb 2008-02-01 05:53|| 2008-02-01 05:53|| Front Page Top

#3 Hmmmm.....

Maybe the people who got the vaccine thought they could engage in more behaviors that would lead to transmission of the infection than those who did not. Not that they'd admit to it.

How's this for an alternate approach. Identify healthy people who have the disease and show no deterioration associated with the disease. They might, just might, have a 'natural' immunity the little bugger can't deal with. Then do a gnome check to see if there are consistent variances between that group and the rest of us. From that develop a prophylactic. Of course that might not involve all the money set aside for academic and medical research that delivered squat for the last two decades. That would be embarrassing.

Posted by Procopius2k 2008-02-01 08:47|| 2008-02-01 08:47|| Front Page Top

#4 Then do a gnome check to see if there are consistent variances between that group and the rest of us.

What if they don't have gnomes in the front yard?

Posted by gorb 2008-02-01 12:06|| 2008-02-01 12:06|| Front Page Top

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