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2022-07-25 Science & Technology

CRISPR gene editing may cause permanent damage - study

[JP] Scientists at Tel Aviv University (TAU) warn that while the CRISPR genome-editing method is very effective, it is not always safe and that sometimes, rearranging pieces of DNA compromises genomic stability, possibly triggering cancer in the long run.

CRISPR – an acronym for “clustered regularly interspaced short palindromic repeats” – allows genetic material to be added, removed or altered at particular locations in the genome. Several approaches to genome editing have been developed.

The best-known technology is called CRISPR-Cas9 gene scissors (CRISPR-associated protein 9), for which the 2020 Nobel Prize in Chemistry was awarded to the American scientist Jennifer A. Doudna and French scientist Emmanuelle Charpentier in recognition of their discovery. Developed about a decade ago, it has already proved impressively effective in treating a range of diseases – cancer, liver diseases, genetic syndromes and more.

Posted by Skidmark 2022-07-25 07:03|| || Front Page|| [11 views ] Top

#1 Cloned BEAGLES are created from gene-edited skin cells for the first time in an attempt to save them from diseases caused by inbreeding

Posted by Skidmark 2022-07-25 08:39|| 2022-07-25 08:39|| Front Page Top

#2 ^^^"We used the DNA from a frog to fill the 'holes'."

Posted by Mullah Richard 2022-07-25 09:31|| 2022-07-25 09:31|| Front Page Top

#3 And now the neurotic little bastitches won't stop eating flies!

Posted by Dron66046 2022-07-25 09:52|| 2022-07-25 09:52|| Front Page Top

#4 If I knew enough about genetics I would have used CRISPR, the fire fly mod pack and the MIT genetic logic pack to modify conifers to flash one month either side of the Winter Solstice .. just to avoid decorating outdoor trees.

Posted by 3dc 2022-07-25 13:54|| 2022-07-25 13:54|| Front Page Top

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