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2021-03-31 Science & Technology

Immune response may explain rare clots after AstraZeneca vaccine

[AlAhram] Researchers may have found an explanation for the rare but serious blood clots reported among some people who received AstraZeneca's COVID-19 vaccine

Scientists believe the phenomenon is similar to one that rarely occurs with a blood thinning drug called heparin, called heparin-induced thrombocytopenia (HIT).

In HIT, the drug triggers the immune system to produce antibodies that activate platelets, which cause blood to clot.

Drugs other than heparin can cause clotting disorders that strongly resemble HIT, and researchers suspect that in rare cases, the AstraZeneca vaccine may be another such trigger.

Four previously healthy individuals who got the AstraZeneca shot and developed life-threatening clots had the same kind of antibodies that activate platelets and initiate clotting in HIT, the researchers reported on Monday in a paper posted on Research Square ahead of peer review.

Twenty individuals who received the vaccine but did not develop clots did not have these antibodies.

An editorial comment posted with the study noted that drug-induced thrombocytopenia is treatable if identified promptly.

Millions of people have received the vaccine without issues.

Posted by trailing wife 2021-03-31 00:00|| || Front Page|| [5 views ] Top

#1 I remember that early in this whole --insert obscene reference here--, there was a paper claiming that the CCP-virus wasn't a respiratory disease, but was actually a blood disease. Having a blood disorder side effect of a vaccine makes sense in that case.

Posted by Mercutio 2021-03-31 07:56|| 2021-03-31 07:56|| Front Page Top

#2 It may well turn out that most of the morbidity caused by COVID-19 comes from an aberrant immune response to the virus. The very low morbidity caused by the virus in the <= 18 age groups may be due to their having the healthiest immune systems of any age group.

Posted by Bubba Lover of the Faeries8843 2021-03-31 17:01|| 2021-03-31 17:01|| Front Page Top

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