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2012-12-31 -Short Attention Span Theater-
Hillary Clinton hospitalized after doctors discover blood clot
[NBC Politics.NBC News] Secretary of State Hillary Clinton
... sometimes described as America's Blond Eminence and at other times as Mrs. Bill, never as Another Charles Evans Hughes ...
was admitted to a New York City hospital on Sunday after doctors discovered that a blood clot had formed, the State Department said in a statement.
Blood clot WHERE?

I've checked multiple news sources and no one says.

Now this is an area within my subspecialty, so permit me to mount my soapbox.

Given what we are told, there are four reasonable potential locations --

1) leg below the knee. That could be due to inactivity stemming from her concussion. We usually do NOT treat these with anti-coagulants. However, 20% of below the knee thrombi will propagate to above the knee so they should be monitored at frequent intervals (ultrasound). We do use NSAIDs, rest and physical therapy.

2) leg above the knee (proximal deep vein thrombosis, DVT). This is a serious medical situation. About 20% of these will break off and cause a pulmonary embolism, and 5 to 20% of those (1 to 4% of all proximal DVT) are fatal. We treat these immediately with a proper anti-coagulant (heparin followed by warfarin or with a low-molecular weight heparin such as Lovenox). A patient usually is hospitalized for a proximal DVT though lately we've had success keeping them at home with daily or twice-daily Lovenox injections. There is some enforced reduction in activity but we don't like to keep people immobile, since immobility is one of the risk factors to get a DVT in the first place.

3) pulmonary embolism (PE). This is serious and can be life-threatening, indeed fatal. These require immediate hospitalization, immediate anti-coagulation, and careful monitoring. There are a number of complications that may occur, from right heart failure to arrhythmias, circulatory collapse, pneumonia, etc.

Both a proximal DVT and PE require a diligent search for why they occurred. The usual causes are 1) advancing age 2) immobility 3) trauma 4) cancer 5) genetic pre-disposition to clotting 6) use of certain medications (e.g., oral contraceptives). Recurrence is common, particularly in the time period following cessation of anti-coagulation (usually done for 6 to 12 months).

4) blood clot within or just above the brain (e.g., subdural hematoma or traumatic brain contusion). If this, the cause is almost certainly trauma from a fall. I note this is how Katherine Graham, past publisher of the Washington Post, died -- she slipped and fell and suffered head trauma with a bleed and clot. These are, of course, extremely serious. Note that head trauma with a bleed/clot is very different than a DVT/PE situation.

So again I repeat my question -- where is the clot?

If #2, #3, or #4, and I were her doctor, she wouldn't be doing anything other than house rest and computer solitaire for a couple weeks until I knew that I had the problem well in hand.

That no one will say, and that we now see that there is and has been a fair bit of the story withheld, and that there has been phony stories put out there (e.g., partying in the Dominican), suggests to me that there is something serious going on.

She's entitled to privacy in her medical affairs as a person. But as Secretary of State, we the public need to know if she can do the job or not.
Philippe Reines, a deputy assistant secretary, said in the statement that the clot stems from a concussion Clinton sustained several weeks ago.

Reines said that Clinton, 65, is being treated with anti-coagulants at New York-Presbyterian Hospital in Manhattan. She will be monitored there for the next 48 hours, he said.

"Her doctors will continue to assess her condition, including other issues associated with her concussion," he said. "They will determine if any further action is required."
Of course they will. Again, where is the clot?
Posted by Fred 2012-12-31 00:00|| || Front Page|| [22 views ]  Top

#1 Isn't warfarin one of the key ingredients in rat poison?
Posted by Rambler in Virginia 2012-12-31 00:11||   2012-12-31 00:11|| Front Page Top

#2 Rat poison indeed Rambler...since rats can't perform a reverse peristalsis (throw up) they ingest the Warfarin (Coumadin as an Rx) and bleed out internally. I've been on the stuff for years due to AF. Careful monitoring is required.

Fred has it right..if this is due to a fall and she is manifesting a subdural hematoma...serous indeed.

Despite our political differences...I wish her a speedy recovery.
Posted by Warthog 2012-12-31 00:23||   2012-12-31 00:23|| Front Page Top

#3 IMA thinking....stroke.
Posted by Besoeker 2012-12-31 00:32||   2012-12-31 00:32|| Front Page Top

#4 --- Much has been withheld.
--- Another possibility: She could have suffered an intimal tear in a carotid or vertebral artery (1) with a clot forming around that or (2) leading to a carotid artery dissection with intramural hematoma.
Posted by Anguper Hupomosing9418 2012-12-31 00:34||   2012-12-31 00:34|| Front Page Top

#5 An arterial tear and clot is possible, particularly after a fall, but many times (not always and not even usually) in that scenario there is an associated stroke (CVA). There's been no report of a stroke. So I think that scenario is less likely, but I wouldn't take it off the table.
Posted by Steve White 2012-12-31 01:05||   2012-12-31 01:05|| Front Page Top

#6 ---Much has been withheld.

Does indeed appear that way. Very FDR'ian. If we begin seeing her in a golf cart....well. I must say however, an impaired Hildebeast would be an improvement over a narcissistic, spiteful Champ.
Posted by Besoeker 2012-12-31 01:17||   2012-12-31 01:17|| Front Page Top

#7 So what you are saying, Besoeker, is that Hillary is being primed for the analog of FDR's third term.

Posted by no mo uro 2012-12-31 06:50||   2012-12-31 06:50|| Front Page Top

#8 If Hillary had a stroke, the general public would be the last to know. I recall Gabby Giffords holding on to her office long after it was obvious she was not up to the job.
Posted by Anguper Hupomosing9418 2012-12-31 09:18||   2012-12-31 09:18|| Front Page Top

#9  long after it was obvious she was not up to the job.

Um AH, how could you tell the difference between the past & the present? That's a fitting description for Shillary from day one.
Posted by AlanC 2012-12-31 09:41||   2012-12-31 09:41|| Front Page Top

#10 The 'Burg is miles ahead of the MSM in quality of reporting on the issue.
Posted by Anguper Hupomosing9418 2012-12-31 10:37||   2012-12-31 10:37|| Front Page Top

#11 NBC claims that blood clots stemming from concussions cannot be treated with blood thinners.

My own observation is that blood clots are frequently associated with frequent flyers and our Secretary of State has most certainly been a frequent flyer.

Posted by Abu Uluque 2012-12-31 11:14||   2012-12-31 11:14|| Front Page Top

#12 What the NBC reporter is saying, and he is correct to say this, is that a clot associated with traumatic brain injury (my scenario #4) is one in which you do NOT treat with anti-coagulants, as that can make the bleeding (which caused the clot) worse. Indeed it can be a fatal mistake.

This is why, when someone has a stroke, we always get a CT or MRI scan prior to starting anti-coagulation: we anti-coagulate for a thrombotic stroke (clot) but not for a hemorrhagic stroke (bleeding).

For a subdural bleed, if she had one as a result of trauma, one would NOT treat with any sort of anti-coagulation whatsoever.

All of this makes me think that she's had a DVT or PE, but it sure would be nice if she and her team (or her BOSS) were forthcoming with details. The last thing we need right now is a crippled Secretary of State.
Posted by Steve White 2012-12-31 11:37||   2012-12-31 11:37|| Front Page Top

#13 "But as Secretary of State, we the public need to know if she can do the job or not."

She never could. How does a blood clot change that?
Posted by Barbara 2012-12-31 11:57||   2012-12-31 11:57|| Front Page Top

#14 How can the docs be so certain she has a blood clot but so uncertain about its location? What kind of generalized symptoms would manifest that would indicate a clot?
Posted by JohnQC 2012-12-31 11:58||   2012-12-31 11:58|| Front Page Top

#15 Fainted, or fell down drunk?
If she had/has a bleeding stroke from the chronic drinking she would certainly be clotting now.
She may also be immobile and speechless.
Posted by Skidmark 2012-12-31 13:18||   2012-12-31 13:18|| Front Page Top

#16 From Instapundit: “The suppression of information — the site of the clot — suggests 2 radically different theories: 1. fakery/exaggeration to evade testimony, or 2. something horribly serious. I read Sepkowitz to exclude the middle ground.”
Posted by Deacon Blues 2012-12-31 14:57||   2012-12-31 14:57|| Front Page Top

#17 Hillary is at NY - Presbyterian in Manhattan.

This is a place with a very good reputation.

They don't admit you unless there is a problem.

They don't shoot you with anti coagulants unless there is a serious reason to do it.
Posted by lord garth 2012-12-31 16:10||   2012-12-31 16:10|| Front Page Top

#18 They found it:

"In the course of a routine follow-up MRI on Sunday, the scan revealed that a right transverse sinus venous thrombosis had formed. This is a clot in the vein that is situated in the space between the brain and the skull behind the right ear. It did not result in a stroke, or neurological damage. To help dissolve this clot, her medical team began treating the Secretary with blood thinners. She will be released once the medication dose has been established. In all other aspects of her recovery, the Secretary is making excellent progress and we are confident she will make a full recovery. She is in good spirits, engaging with her doctors, her family, and her staff."
Posted by trailing wife 2012-12-31 17:32||   2012-12-31 17:32|| Front Page Top

#19 Heck, she may never be able to testify. How unfortunate - for the country. She will never be held accountable.

She should stay out of Ft Marcy Park, and away from buses.
Posted by Rambler in Virginia 2012-12-31 17:33||   2012-12-31 17:33|| Front Page Top

#20 Looks like Fred's Case#4.
Posted by Skidmark 2012-12-31 18:03||   2012-12-31 18:03|| Front Page Top

#21 "She is in good spirits(perhaps sedated), engaging(possible eye movement, but not speaking) with her doctors, her family, and her staff."
Posted by Skidmark 2012-12-31 18:14||   2012-12-31 18:14|| Front Page Top

#22 Looks like Fred's Case#4.

The comments in pi--er, salmon--are from Dr. Steve White.
Posted by Angie Schultz 2012-12-31 18:28||   2012-12-31 18:28|| Front Page Top

#23 Fell up a flight of stairs, slipped on the toilet, and bonked her noggon on the showerhead, she did.
Posted by swksvolFF 2012-12-31 18:57||   2012-12-31 18:57|| Front Page Top

#24 "She is in good spirits(perhaps sedated), engaging(possible eye movement, but not speaking) with her doctors, her family, and her staff."

Bill: "Best New Years Eve, evah! C'mon honey, Hillary's not coming home tonight..."
Posted by Frank G 2012-12-31 19:11||   2012-12-31 19:11|| Front Page Top

#25 "Mr. Clinton, we can bring in a cot so you can stay with Mrs. Clinton if you'd like?"
"Heh...on New Yeah's Eve? Ah don't think so, hunny. Y'all got plans fer the night? Ah always had a thang fer nurses..."
Posted by tu3031 2012-12-31 19:24||   2012-12-31 19:24|| Front Page Top

#26 just hope tonight's "dates" are willing
Posted by Frank G 2012-12-31 19:49||   2012-12-31 19:49|| Front Page Top

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