[Ynet] Preliminary findings from a study at the Davidoff Center at Rabin Medical Center suggest a novel treatment may eradicate rectal cancer in 65% of patients and reduce the need for surgery. Led by Prof. Baruch Brenner, head of the Oncology Department and the Gastrointestinal Oncology Unit, the study presents a potential new direction in cancer treatment. "These results suggest a promising new direction," said Prof. Brenner.
Rectal cancer, accounting for about 25% of colorectal cancer cases, is often diagnosed at an advanced stage, requiring complex treatment. Traditional treatment for localized rectal cancer typically involves surgery, which can significantly impact a patient's quality of life, sometimes necessitating the removal of the anus. The new approach combines immunotherapy with chemoradiotherapy, potentially eliminating the need for surgery in many cases.
Conducted with a team of specialists at Rabin Medical Center, the study found that preoperative immunotherapy and chemoradiotherapy substantially improve the likelihood of curing rectal cancer and reducing surgical necessity.
Preliminary results involving 20 out of 29 patients were presented at the European Society for Medical Oncology (ESMO) Gastrointestinal Tumors Conference in Munich. The combined treatment eradicated tumors in 65% of patients and prevented surgery for most.
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