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| Science & Technology |
| Combo ‘polypill' cuts heart disease deaths, new study finds |
| 2022-08-28 |
| [NYP] One pill may be better than three. A yuge letdown for Big Pharma and the VAX crowd. Bill and Melinda are not going to be pleased with this development either. A heart medication known as a "polypill" reduced the chance of a secondary adverse cardiovascular event in individuals who previously had a heart attack, according to the findings of a study announced on Friday, August 26, at the European Society of Cardiology Congress (ESC 2022) in Barcelona, Spain. The cardiovascular mortality rate was lowered by 33%, the study found. While too late for many, ten percent would have been wonderful. Published in The New England Journal of Medicine, the study found that the drug, bearing the commercial name Trinomia, contains three medications: aspirin (100 mg), the angiotensin-converting enzyme inhibitor ramipril (2.5, 5, or 10 mg) and atorvastatin (20 or 40 mg), according to a news release. The Spanish National Center for Cardiovascular Research (CNIC) and Ferrer developed the polypill. Unlike the CDC, the CNIC appears to be interested in prevention and cures. Currently, the polypill is not available in the United States. Dr. Valentin Fuster, M.D., director of Mount Sinai Heart and physician-in-chief of Mount Sinai Hospital as well as general director of CNIC, led the trial. There it is again! That pesky Jewish philanthropist Simpson is to blame for all of this progress. The study’s results demonstrate "for the first time that the polypill — which contains aspirin, ramipril and atorvastatin — achieves clinically relevant reductions in the recurrent cardiovascular events among people who have recovered from a previous heart attack," he said in the release. |
| Posted by:Besoeker |
| #13 I took up golf after my first heart attack. I now shot 68 for 9 holes. |
| Posted by: Bob Whaiger9805 2022-08-28 16:06 |
| #12 You know B, you could take up golf instead, and like most older people, who get their first Hole-in-One at the ripe old age of 82, have that "coming to join you Elizabeth" moment out on the fairway. |
| Posted by: Neville Unavitle4308 2022-08-28 15:27 |
| #11 Remember B, He also serves who stands and waits! |
| Posted by: NoMoreBS 2022-08-28 14:47 |
| #10 ^ Same and same. |
| Posted by: The Walking Unvaxed 2022-08-28 14:31 |
| #9 I want to go in my sleep, up in a deer stand. Turkey Buzzard bait for six months or so, or until they find me. Unfortunately Gawd only has so many deer stand tickets. Not certain my unextraordinary duty performance warrants one :-( |
| Posted by: Besoeker 2022-08-28 14:11 |
| #8 Gee, and I was really hoping Ivermectin would cut the mustard. |
| Posted by: DooDahMan 2022-08-28 14:06 |
| #7 What's the word? Thunderbird? What's the price? A dollar, twice. Who drinks the most? ... |
| Posted by: M. Murcek 2022-08-28 13:48 |
| #6 While I am not a MD, I would recommend occasionally taking some MD-2020 - may not help your heart, but you'll feel real good right before your heart attack... |
| Posted by: Neville Unavitle4308 2022-08-28 13:29 |
| #5 Low dose Aspirin has been stopped by my cardiologist. Similarly among others as well. I am not up to date on what happened but I assume it was of no benefit. |
| Posted by: Dale 2022-08-28 09:12 |
| #4 Swap out Lisonipril for Ramipril, then those three are what I'm taking now. |
| Posted by: Raj 2022-08-28 08:56 |
| #3 Thanks TOTW. Thanks WIKI. Ramipril, sold under the brand name Altace among others, is an ACE inhibitor type medication used to treat high blood pressure, heart failure, and diabetic kidney disease. Wikipedia Formula: C23H32N2O5 Classification: ACE inhibitor Metabolism: Liver, to ramiprilat Protein binding: 73% (ramipril); 56% (ramiprilat) AHFS/Drugs.com: Monograph ATC code: C09AA05 (WHO) Elimination half-life: 13 to 17 hours Atorvastatin Common brands: Lipitor Statin It can treat high cholesterol and triglyceride levels. This may reduce the risk of angina, stroke, heart attack, and heart and blood vessel problems. Brands: Lipitor Availability: Prescription needed Pregnancy: Consult a doctor Alcohol: Interactions can occur |
| Posted by: Besoeker 2022-08-28 08:10 |
| #2 All three medications are available separately, so the advantage is just that they are combined into one pill. |
| Posted by: Too Old To Work 2022-08-28 08:05 |
| #1 Currently, the polypill is not available in the United States. The major component is the inexpensive, newly developed drug Aspirin. Who knew? Approval however, may take years even decades. |
| Posted by: Besoeker 2022-08-28 04:55 |