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Science & Technology
Why all the fuss about Ivermectin?
2021-09-03
[American Thinker] First hydroxychloroquine, now ivermectin, is the hated deadly drug de jour, castigated by the medical establishment and regulatory authorities. Both drugs have been around for a long time as FDA-approved prescription medications. Yet now we are told they are as deadly as arsenic.

As a physician, I am certainly aware of ivermectin but don’t recall ever writing a prescription for it in my 30+ years’ medical career. Ivermectin is an anthelmintic, meaning it cures parasitic infections. In my world of ophthalmology, it is used on occasion for rare parasitic or worm infections in the eye.

Ivermectin was FDA approved in 1998 under brand name Stromectol, produced by pharmaceutical giant Merck, approved for several parasitic infections. The product label described it having a "unique mode of action," which "leads to an increase in the permeability of the cell membrane to chloride ions." This suggests that ivermectin acts as an ionophore, making cell membranes permeable to ions that enter the cell for therapeutic effect.

Ivermectin is one of several ionophores, others including hydroxychloroquine, quercetin, and resveratrol, the latter two available over the counter. These ionophores simply open a cellular door, allowing zinc to enter the cell, where it then interferes with viral replication, providing potential therapeutic benefit in viral and other infections.

This scientific paper reviews and references other studies demonstrating antibacterial, antiviral, and anticancer properties of ivermectin. This explains the interest in this drug as having potential use in treating COVID.

Does ivermectin work in COVID? I am not attempting to answer that question, instead looking at readily available information because this drug has been the focus of much recent media attention. For the benefit of any reader eager to report this article and author to the medical licensing boards for pushing misleading information, I am not offering medical advice or prescribing anything. Rather, I am only offering commentary on this newsworthy and controversial drug.

What’s newsworthy about ivermectin? A simple Google search of most medications describes uses and side effects. A similar search of ivermectin provides headlines of why it shouldn’t be taken and how dangerous it is.
Related:
Ivermectin: 2021-09-01 HHS Amends PREP Act Liability Waiver To Cover Only NIH Approved Treatments for COVID-19
Ivermectin: 2021-08-26 Arkansas detention center doctor is treating COVID positive inmates with cow deworming drug FDA warns is dangerous – as people in Oklahoma flock to feed stores to buy it
Ivermectin: 2021-08-23 'You are not a cow!' FDA warns Americans to stop taking livestock de-wormer drug Ivermectin as an unproven treatment for COVID-19
Posted by:Besoeker

#18  Tired of This "Horse" Shit, or, Malice in Wonderland?

I went down to St. Squirmer's Infirmary
But heard -- not from worm or from germ
Or from Pravda or Stürmer --
Not one timid murmur
Of something called "African wormer."
Posted by: Chusoting Clomoting4647   2021-09-03 19:07  

#17  I do not share your touching faith in any data coming from the PRC.

Are you claiming that they're not locking down cities?
Well, old boy, do have your horse dewormer in lieu of vaccination. I'm sure it'll do you a word of good.
Posted by: g(r)omgoru   2021-09-03 16:58  

#16  #13 We have a treatment - it's called vaccination. People who refuse vaccination and get Covid should, IMO, be treated with the snake oil of their choice - and charged for the treatment.
Posted by: g(r)omgoru   2021-09-03 16:50  

#15  
if there was a miracle cure - the Chinese (who are not bound by medical ethics in experimenting on humans) would have discovered it some time ago. And, if they had miracle cure, they would not be locking down cities of 10 million people

I do not share your touching faith in any data coming from the PRC.
Posted by: Bubba Lover of the Faeries8843   2021-09-03 16:37  

#14  #12 most effects discovered in vivo vitro don't work in vitro vivo.
(long day).
Posted by: g(r)omgoru   2021-09-03 16:30  

#13  The point I was trying to make is, remdesivir isn't just not a miracle-cure, it's reportedly actively harmful.

The people who were actually using hcq to treat C19 were using it in conjunction with azithromycin and zinc, and at much lower dosages than the studies that showed it didn't work.
Posted by: Thing From Snowy Mountain   2021-09-03 16:23  

#12  #2 Thing, which part of "component of treatment =/= miracle cure" you don't understand?
As I endeavored to explain to you some time hence, if there was a miracle cure - the Chinese (who are not bound by medical ethics in experimenting on humans) would have discovered it some time ago. And, if they had miracle cure, they would not be locking down cities of 10 million people - no matter how hard Fauci (666) would beg them.

#11 Robert, can I suggest
Studies Show Zinc Inhibits Viral Replication, but There's a Catch

Incidentally, if you go to google scholar and type "zinc ionophore covid" you get 1,660 results - so, don't tell me the subject is suppressed.

As to HCQ specifically, prey read the abstract of Chloroquine and Hydroxychloroquine: Efficacy in the Treatment of the COVID-19

Let me share something with you: most effects discovered in vivo don't work in vitro.
Posted by: g(r)omgoru   2021-09-03 15:48  

#11  Here's the HCQ/Iverm/zinc connection - Ivermectin is one of several ionophores, others including hydroxychloroquine, quercetin, and resveratrol, the latter two available over the counter. These ionophores simply open a cellular door, allowing zinc to enter the cell, where it then interferes with viral replication,

I also note my Sonovia mask has zinc embedded in the fabric, which Sonovia's test results say kills the virus.
Posted by: Bobby   2021-09-03 15:03  

#10  Thanks TW.
Posted by: Besoeker   2021-09-03 12:54  

#9  Reservatrol is a nutraceutical found in the vitamin section of your grocery store or drug store, so no need for a doctor’s prescription to take it. It’s derived from grape skins, one of the reasons red wine is touted as healthier than white. I take it as part of my daily routine, independent of Covid concerns.

A blog post on the subject from my favourite mail order supplement company: link
Posted by: trailing wife   2021-09-03 12:51  

#8  CDC endorsed use of ivermectin … for Afghan refugees!
Posted by: Angstrom   2021-09-03 12:04  

#7  1. The FDA cannot issue an emergency use authorization if a treatment is available.

2. You can't have a pandemic (and scare people witless) if there is a safe and effective treatment.
Posted by: Angstrom   2021-09-03 11:55  

#6  Saw a good comment elsewhere: Ivermectin is "horse paste" just as amoxicillin is moldy fruit.
Posted by: M. Murcek   2021-09-03 11:17  

#5  Were the results of the resveratrol trial published anywhere?
Posted by: Thing From Snowy Mountain   2021-09-03 10:47  

#4  
Last year, my son, a Firefighter/EMS 1st Responder after running dozens of Covid-19 calls a night he and 2 others came down with it. When they ended up in the same Metro Atlanta Hospital ER where they were admitted.

Because of his demographics he was offered and accepted to be a Test Group candidate for ?Resveratrol? medication.

He and 1 other were released 48 hours later and sent home for 12 more days of county/state mandatory butt time.

The 3rd refused and was sick for several additional hospitalized days according to what we were told.

His 1st Hand exp. is:
It help to greatly reduce the overall serious issues and reduced the need for a much needed hospital bed.




Posted by: NN2N1   2021-09-03 09:51  

#3  Alternative FDA approved usage of medicines has been utilized for many years. Prescriptions for non approved FDA medicines is or was historically malfeasance. I suppose what presented the greatest threat to the pharmaceutical industry attracted the greatest ire. So what is shown to work in my opinion use it. That is the judgement of the attending physician. The FDA is lethargic at best. Smearing of others is a technique long held dear by the weak and control oriented. I see the choice now is between the red pill or the blue pill. The choice has been made for many and no argument will sway one from another in their way of thinking.
Posted by: Dale   2021-09-03 09:11  

#2  I have another question for you.

YOU say that all the drugs are useless, including Remdesivir.

Did you know that Remdesivir is an approved treatment _in Israel_?
Posted by: Thing From Snowy Mountain   2021-09-03 09:09  

#1  Because Covid treating MDs are too busy to suffer fools gladly?
Posted by: g(r)omgoru   2021-09-03 06:16  

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