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| Science & Technology |
| Correlation of SARS-CoV-2 Breakthrough Infections to Time-from-vaccine; Preliminary Study |
| 2021-08-22 |
| [MedRxiv] - The short-term effectiveness of a two-dose regimen of the BioNTech/Pfizer mRNA BNT162b2 severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine was widely demonstrated. However, long term effectiveness is still unknown. A nationwide vaccination campaign was initiated early in Israel, allowing for a real-world evaluation of the interaction between protection and time-from-vaccine. The Delta (B.1.617.2) variant became the dominant strain in Israel in June 2021, as Israel is currently experiencing a new surge of cases. Leveraging the centralized computerized database of Maccabi Healthcare Services (MHS), we assessed the correlation between time-from-vaccine and incidence of breakthrough infection. We found that the risk for infection was significantly higher for early vaccinees compared to those vaccinated later. This preliminary finding should prompt further investigagions into long-term protection against different strains, and prospective clinical trials to examine the effect of a booster vaccine against breakthrough infection. In other words, the protection is temporary. |
| Posted by:g(r)omgoru |
| #8 It was known to be a single strand virus, which are far more likely to mutate more often. This was talked about right after the DNA was sequenced. Why are people acting surprised now? Also reminder that correlation is not causation, so be careful about jumping to conclusions. |
| Posted by: Greater the Anonymous5721 2021-08-22 14:45 |
| #7 It is a virus. It will always mutate rapidly and get around our defenses. They have for billions of years and we will always be one step behind and reacting. Putting a nation on lockdown because of it is stupid and cultural and economic suicide. |
| Posted by: DarthVader 2021-08-22 10:23 |
| #6 ^^^ Thank you - finally someone (a guy living in Georgia) gets it. I appreciate your clarity and candor (applause 👏) |
| Posted by: Thrailing Untervehr4604 2021-08-22 08:50 |
| #5 So, as many here have said very early on. The C-19(?) seems to be like a Seasonal Flu and questioned whether Shots would cover all strains? Either way, the C-19 has already mutated 2x in just 3 months and now a 5th time in 8 months since Nov. 2019 with the C-19(I) strain. But unlike the Old Normal season based Flu. The "New Normal" C-19(?)seems to do well year round and much better in some months. Which sounds like the US population will be expected to line up for the most recent, not fully tested, Government provided Fix every few months. Pretty soon whoever controls the Vax and Needle supplies will be the actual ones in charge. |
| Posted by: NN2N1 2021-08-22 08:36 |
| #4 Fauxi: "I know what, let's do gain of function research on something we already know is difficult to innoculate against effectively." The research community: "Tony, we are in awe. Ideas like that are why you get the big bucks..." |
| Posted by: M. Murcek 2021-08-22 06:54 |
| #3 #1 Yes. To recollect: 35 Years of Research Into Coronavirus Infections Show Long-Term Immunity Is Unlikely |
| Posted by: g(r)omgoru 2021-08-22 05:00 |
| #2 Early vaccinees are the most vulnerable. |
| Posted by: boomerc 2021-08-22 04:12 |
| #1 And not only is the protection temporary, the decline in protection is not due to the change in virus strain (or at least that's how I read this.) |
| Posted by: Glenmore 2021-08-22 03:33 |