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Science & Technology
There's a disturbing new link between gum disease and dementia
2021-04-13
[NYT] Healthy molars, healthy mind.

In case oral hygiene wasn’t important enough already, brushing one’s teeth could help maintain one’s mental — along with their dental — health.

A recent study found a correlation between gum disease and dementia and other brain diseases, the Daily Mail reported. Prior studies had found that bacteria-causing gingivitis can metastasize from the mouth to the brain.

"This is the first study showing an association between the imbalanced bacterial community found under the gumline and a cerebrospinal fluid biomarker of Alzheimer’s disease in cognitively normal older adults," explained Dr. Angela Kamer of the NYU Dentistry School. She authored the brainy study published in Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring.

Previous studies had established a link between a buildup of amyloid proteins in the cerebral arteries and cognitive decline. However, researchers had yet to pinpoint how that amyloid buildup causes the disease, which they now theorize could occur when gum disease prevents the body from jettisoning these interloping enzymes from the brain.

Researchers attempted to prove the dental-mental wellness connection by taking both gum swabs and cerebrospinal fluid samples from 48 healthy volunteers over 65 years old. People in this age group face a high risk of both dementia and gum disease — a cautionary tale for notoriously dentist-averse millennials.

They then measured their amounts of good and bad oral flora and found that individuals with more beneficial mouth microbes had lower levels of amyloids. In turn, these individuals had a lesser chance of contracting dementia.
Posted by:Besoeker

#3  Sorry. My dad was borderline OCD and brushing his teeth regularly was definitely happening. It's genetic, and if it's in your family history you had better plan accordingly.
Posted by: M. Murcek   2021-04-13 14:09  

#2  Looking back at the history of medicine & dentistry -- 1800-1910 or so - old timey docs were big on full mouth extractions and full dentures when teeth & gums (consider them a unit) got hopelessly rotten & inflamed. As best I can figure out from what records there are, this was often followed by an increase in the patient's sense of well being.
In my own family, several elders passed that point back in the 1950s and 1960s, and had their own full mouth extraction & fitment for full dentures. Without exception every one of these former dental patients stated their sense of well being improved as soon as their mouths healed, and this persisted for decades afterwards. They also welcomed the fact that they never again needed to see a dentist. Perhaps they needed to see a denturist to adjust the dentures afterward but some of them didn't even need that.
So do consider that trying to be healthy with a mouthful of decay, infection and inflammation might just be futile.
Posted by: Bubba Lover of the Faeries8843   2021-04-13 11:20  

#1  Been reading a lot lately about links to dementia; last one was snoring and dementia. The commonality is that the supposed "links" are all age-related. I suspect these are age-related comorbidities, not causes.

Correlation is not causation said someone sometime.
Posted by: Mercutio   2021-04-13 07:17  

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