[AlAhram] The World Health Organization (WHO) said on Saturday that it was discontinuing its trials of the malaria drug hydroxychloroquine and combination HIV drug lopinavir/ritonavir in hospitalised patients with COVID-19 after they failed to reduce mortality."These interim trial results show that hydroxychloroquine and lopinavir/ritonavir produce little or no reduction in the mortality of hospitalised COVID-19 patients when compared to standard of care.
...if it is hydroxychloroquine alone and only on hospitalized patients, it’s no wonder they aren’t getting a positive result...
Solidarity trial Sherlocks will interrupt the trials with immediate effect," the WHO said in a statement, referring to large multi-country trials that the agency is leading.The U.N. agency said that the decision, taken on the recommendation of the trial's international steering committee, does not affect other studies where the drugs are used for non-hospitalised patients or as a prophylaxis.
So that’s ok, then. Not that the smart money is on the WHO being the leading edge of scientific research anymore.
Another arm of the WHO-led trial is looking at the potential effect of Gilead's antiviral drug remdesivir on COVID-19.Related:
Hydroxychloroquine: 2020-07-04 HCQ Success in Senegal
Hydroxychloroquine: 2020-07-03 Hydroxychloroquine lowers COVID-19 death rate, Henry Ford Health study finds
Hydroxychloroquine: 2020-07-01 Global Hydroxychloroquine Study To Resume After Positive Trial Results
Hydroxychloroquine: 2020-07-04 HCQ Success in Senegal
Hydroxychloroquine: 2020-07-03 Hydroxychloroquine lowers COVID-19 death rate, Henry Ford Health study finds
Hydroxychloroquine: 2020-07-01 Global Hydroxychloroquine Study To Resume After Positive Trial Results