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Home Front: Culture Wars
Here's Why A Coronavirus Vaccine Might Not Happen Within 18 Months
2020-04-19
We always knew this. Timelines for upstream discoveries are nothing more than hope until something proves out. It’s the downstream side of things that is predictable. But while a vaccine would be awfully nice, the key is to have workable treatments for those who need them.
[ZeroHedge] With much of the world under some form of lockdown to slow the spread of COVID-19, and debates rage over when, and how, to reopen the global economy in order to avoid the next great depression, the light at the end of the tunnel has been top-down predictions of a vaccine within 18 months.

JPMorgan, for example, makes a core assumption that "it could take 12-16 months for a vaccine to be under mass production," and that the US will go through cycles of increased distancing measures followed by virus flare-ups, which require more lockdowns.

Yet after bold predictions and vaccines rumored to be 'just around the corner,' Dr. Anthony Fauci, director of the US National Institute of Allergy and Infectious Disease who sits on President Trump's coronavirus task force, offered a less enthusiastic view - saying in early March that a vaccine might be available in 12 - 18 months.

"The whole process is going to take a year, a year and a half, at least," said Fauci.

And while Fauci has been accused of fear mongering - relying on wildly-pessimistic models while advising President Trump on lockdown measures, he may have been wise to downplay the vaccine timeline.

According to a new report by Australia's ABC, the creation of a vaccine may be incredibly difficult for several reasons, as this particular coronavirus is 'posing challenges that scientists haven't dealt with before.'

According to Ian Frazer of the University of Queensland - who was involved in the creation of the HPV vaccine, coronaviruses are particularly difficult to create safe vaccines before because the virus infects the upper respiratory tract, which our immune system isn't particularly adept at protecting.
There are several reasons why our upper respiratory tract is a hard area to target a vaccine.

"It's a separate immune system, if you like, which isn't easily accessible by vaccine technology," Professor Frazer told the Health Report.

Despite your upper respiratory tract feeling very much like it's inside your body, it's effectively considered an external surface for the purposes of immunisation.

"It's a bit like trying to get a vaccine to kill a virus on the surface of your skin." -ABC News

In other words, because the upper respiratory tract is effectively "outside" of the body, and the outer layer of (epithelial) cells in the tract is our natural barrier to viruses, it's difficult to produce an immune response which can reach them.

Complicating matters is that if a vaccine causes an immune response that doesn't benefit the target cells, the result could potentially be worse than no vaccine at all.
Posted by:Iblis

#17  At this point there are bug worshippers. The bug is omnipotent, you must comply your life to the bug. Sad what people latch onto when they see nothing bigger than themselves.
Posted by: M. Murcek   2020-04-19 17:54  

#16  ^ Which makes no sense. Typical overreach by Sheriff Bill "FBI" Gore
Posted by: Frank G   2020-04-19 17:16  

#15  Besoeker, a parade like that would be illegal right now in San Diego. Surfing, swimming and recreational boating is prohibited in public waters all up and down the coast.
Posted by: Abu Uluque   2020-04-19 17:02  

#14  Boaters participated in a parade in support of the president over the weekend in the Hillsboro Beach Intracoastal waterway, located about 30 miles south of Trump’s Mar-a-Lago resort.
Posted by: Besoeker   2020-04-19 16:47  

#13  /\ I don't care when it comes out, I'm not taking it.

Nor will I, but for legal purposes.... I'll be adding it to my old yellow 731 (shot record). Morgan & Morgan will need something to add me to the action.
Posted by: Besoeker   2020-04-19 16:34  

#12  I don't blame you.
Posted by: Clem   2020-04-19 16:30  

#11  I don't care when it comes out, I'm not taking it.
Posted by: 49 pan   2020-04-19 16:29  

#10  ^Because they don't make any money if vaccine doesn't work and developing one costs quite a lot.
Posted by: g(r)omgoru   2020-04-19 15:33  

#9  Could put the question another way Elmerert, are 60 or so companies around the world working on a vaccine are all idiots?
Posted by: g(r)omgoru   2020-04-19 15:32  

#8  "It's a bit like trying to get a vaccine to
kill a virus on the surface of your skin."


Bad comparison. The upper layer of the human skin consists of dead cells.

Some questions:

The flu is initially a respiratory tract infection. How do flu vaccines overcome the problem stated in in the article?

The China virus sometimes affects the kidneys, the brain and the gastrointestinal tract.

If a vaccine couldn't prevent the upper respiratory tract infection that is similar to the common cold but protect against complications affecting the inner organs wouldn't that be worthwhile as a stopgap measure?
Posted by: Elmerert Hupens2660   2020-04-19 15:26  

#7  You want to be first to get it? I don't. What will they do, set up internment camps? Bring it.
Posted by: M. Murcek   2020-04-19 10:25  

#6  Jumping right ahead here, since it won't be possible to vaccinate 300+ million people all at once, it's going to be interesting to see who gets the vaccine first. Surely our senior civil servants will be willing to go last so that more vulnerable populations can go first. Then again, maybe not.
Posted by: Matt   2020-04-19 10:13  

#5  The people who laugh and rub their hands together when one of Trump's immigration orders is overturned by judicial fiat better get ready for what happens in the courts when a "mandatory" vaccine arrives.
Posted by: M. Murcek   2020-04-19 08:25  

#4   OMG! We're all gonna die!

Net Neutrality repeal killed me already, and then the Trump tax cuts finished me off!
Posted by: Raj   2020-04-19 06:25  

#3  p.s. I understood that upper respiratory tract infection is the last stage of the serious form.
Posted by: g(r)omgoru   2020-04-19 03:59  

#2  One of the good things from coronavirus, we'll have new, rapid, methodology of creating vaccines.
Posted by: g(r)omgoru   2020-04-19 03:56  

#1  OMG! We're all gonna die!

But don't worry - it'll be Trump's fault.
Posted by: Bobby   2020-04-19 00:53  

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