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| Science & Technology |
| No Flowers for 🐁 Algernon Instead Send to Cliff Robertson aka Charly, Author Daniel Keyes |
| 2020-12-29 |
| [GoodNewsNetwork] Just a few doses of an experimental drug that reboots protein production in cells can reverse age-related declines in memory and mental flexibility in mice, according to a new study by UC San Francisco scientists. The drug, called ISRIB, has already been shown in laboratory studies to restore memory function months after traumatic brain injury (TBI), reverse cognitive impairments in Down Syndrome, prevent noise-related hearing loss, fight certain types of prostate cancer, and even enhance cognition in healthy animals. In the new study, published Dec. 1 in the open-access journal eLife, researchers showed rapid restoration of youthful cognitive abilities in aged mice, accompanied by a rejuvenation of brain and immune cells that could help explain improvements in brain function—and with no side effects observed. “ISRIB’s extremely rapid effects show for the first time that a significant component of age-related cognitive losses may be caused by a kind of reversible physiological “blockage” rather than more permanent degradation,” said Susanna Rosi, PhD, Lewis and Ruth Cozen Chair II and professor in the departments of Neurological Surgery and of Physical Therapy and Rehabilitation Science. “The data suggest that the aged brain has not permanently lost essential cognitive capacities, as was commonly assumed, but rather that these cognitive resources are still there but have been somehow blocked, trapped by a vicious cycle of cellular stress,” added Peter Walter, PhD, a professor in the UCSF Department of Biochemistry and Biophysics and a Howard Hughes Medical Institute investigator. “Our work with ISRIB demonstrates a way to break that cycle and restore cognitive abilities that had become walled off over time.” |
| Posted by:ee green |
| #6 Speaking of side effects, listen to Gates him & haw for about a minute and thirty seconds when posed a real question by a real MSM person, Norah O'Donnell. What a piece of egesta our newly ordained expert is. |
| Posted by: Clem 2020-12-29 21:21 |
| #5 Neither of which are as scary as Congress operating on fify... |
| Posted by: Anomalous Sources 2020-12-29 20:18 |
| #4 The book it was a sudden sharp decline in cognitive abilities and death. In movies and video games, it is the plot point for zombie origin. Neither of which are as scary as Congress operating on all cylinders. |
| Posted by: swksvolFF 2020-12-29 15:21 |
| #3 One wonders about side effects. Also, how much will it cost? |
| Posted by: trailing wife 2020-12-29 13:57 |
| #2 I'd say make it available to Congress but you can't fix stupid and there is no vaccine for evil. |
| Posted by: Warthog 2020-12-29 09:28 |
| #1 One of the greatest SF stories. |
| Posted by: g(r)omgoru 2020-12-29 02:20 |